The company has 44 major research projects of 16 major drug candidates, of which eight indications / four drug candidates (Donafenib Tablet, Recombinant Human Thrombin for Topincal Use, Jacktinib Tablet and Recombinant Human Thyroid-stimulating Hormone for Injection) are in the NDA, Phase III or registration clinical trial stages. Five drug candidates, Jacktinib Cream, Obeticholic Acid Magnesium Tablet, ZG19018 Tablet, ZG005 Powder For Injection and Alkotinib Capsule, are under Phase I/II clinical trial stages. Seven drug candidates are in the IND review stage or preclinical development stage.
The Company is continually improving its R&D technology platforms to optimize and develop its pipeline through in-house R&D and external cooperation and prioritizing for product advancement, differentiation and commercialization. The company focuses on tumors, hemorrhagic and bleeding diseases and hepatobiliary diseases, and actively builds and strengthens its long-term competitiveness in the field of tumor, especially liver cancer treatment. Current clinical trials of the combination of its targeted small molecule drugs, including Donafenib, with immunotherapy antibody drugs like anti-PD-1/PD-L1 antibodies are going. Expanding upon this experience, the Company is developing new generation of immunotherapeutic antibody drugs and their combo-use. In addition, the company is developing a number of blood hemostasis products applicable to multiple hemorrhage conditions. Beyond a robust pipeline, the Company is also establishing a wide range of partnerships both in China and abroad that will greatly increase the geographical opportunities for our business.
The Company's drugs currently in research and development are shown below: